rotaxane

www.rotaxane.net

2012

"Template synthesis of molecular knots", J-F Ayme, J E Beves, C J Campbell and D A Leigh, Chem Soc Rev, published online 13 August 2012.
"A scalable synthesis of 5,5'-dibromo-2,2'-bipyridine and its stepwise functionalization via Stille couplings", D M D'Souza, D A Leigh, M Papmeyer and S L Woltering, Nature Protocols, 7, 2022–2028 (2012).
"Pentameric Circular Iron(II) Double Helicates and a Molecular Pentafoil Knot", J-F Ayme, J E Beves, D A Leigh, R T McBurney, K Rissanen and D Schultz, J Am Chem Soc, 134, 9488-9497 (2012).
"A Three-Compartment Chemically-Driven Molecular Information Ratchet", A Carlone, S M Goldup, N Lebrasseur, D A Leigh and A Wilson, J Am Chem Soc, 134, 8321-8323 (2012).
[For a highlight of this paper see: 'Ratcheting up to a molecular motor' JACS Spotlight, June 2012.]
"A Small Molecule That Walks Non-Directionally Along a Track Without External Intervention", A G Campaña, A Carlone, K Chen, D T F Dryden, D A Leigh, U Lewandowska and K M Mullen, Angew Chem Int Ed, 51, 5480–5483 (2012). Featured on the cover of Angew Chem Int Ed.

[For highlights of this paper see: 'On the right track' Nature Chem, 4, 430-431 (2012); 'Walk on by: The light at the end of the track' D Bradley, SpectroscopyNow, 15 May 2012; 'A Two-Legged Molecule' Angew Chem Int Ed press report, 24 April 2012.]
"Half-Rotation in a Kinetically Locked [2]Catenane Induced By Transition Metal Ion Substitution", D A Leigh, P J Lusby, A M Z Slawin and D B Walker, Chem Commun, 48, 5826-5828 (2012).
"A Rotaxane-Based Switchable Organocatalyst", V Blanco, A Carlone, K D Hänni, D A Leigh and B Lewandowski, Angew Chem Int Ed, 51, 5166-5169 (2012).
[For highlights of this paper see: 'Switchable catalysis' U Lüning, Angew Chem Int Ed, published online 23 July 2012; 'Controlling an organocatalyst with pH' Chem World, 19 April 2012.]
"Second Generation Specific-Enzyme-Activated Rotaxane Propeptides", A Fernandes, A Viterisi, V Aucagne, D A Leigh and S Papot, Chem Commun, 48, 2083-2085 (2012).
[Selected as a Chem Commun "Hot Article" 2012]
"A Synthetic Molecular Pentafoil Knot", J-F Ayme, J E Beves, D A Leigh, R T McBurney, K Rissanen & D Schultz, Nature Chem, 4, 15-20 (2012). Full Article. News & Views. How it works. Hologram. Featured on the front cover of Nature Chemistry issue 1, 4 (2012).

[For highlights of this paper see: 'One-pot pentaknot (N&Vs)' M. J. Hardie, Nature Chem, 4, 7-8 (2012); 'Molecule tied in pentafoil knot' Chem & Eng News, 89(45), 25 (2011); 'Single molecule ties its way into famous knot' New Scientist, 7 Nov 2011; 'Edinburgh atom weaving could strengthen plastic' BBC News, 7 Nov 2011; 'Scots team weaves way to stronger plastics' The Scotsman, 7 Nov 2011; 'Scots breakthrough could lead to creation of stronger plastics' The Herald, 7 Nov 2011; 'Molecule ties itself in a complex knot' Science News, 29 Dec 2011; 'New technique holds promise for lighter, stronger plastics' Eureka magazine, 7 Nov 2011; 'Atom weaving breakthrough hailed' Yahoo! News, 6 Nov 2011; 'Chemists create world’s most complex molecular knot' R&D magazine, 7 Nov 2011; 'Weaving atoms into star-shapes can produce stronger plastics, say Scots scientists' Daily Record, 7 Nov 2011; 'Scientists hail atom-weaving breakthrough' World News Australia, 7 Nov 2011; 'Des noeuds dans les molecules' (in French) La Recherche, Jan 2012, p15; 'Knot too shabby' The Scottish Sun, 7 Nov 2011; 'Mary Erskine and Stewart's Melville Junior School P6C "Positive People" Nomination', 14 Nov 2011; Radio interview with Professor Leigh BBC Radio Scotland, Newsdrive, 7 Nov 2011; 'Knotted molecule' Chem World, Dec 2011; 'Cutting-edge chemistry in 2011' Chem World, 20 Dec 2011; 'Image of the Year' Diamond Light Source, 21 Dec 2011; 'A synthetic molecular pentafoil knot' DLS Annual Report 2012, p89-90; etc.]
"Time-Resolved Vibrational Spectroscopy of a Molecular Shuttle", M R Panman, P Bodis, D J Shaw, B H Bakker, A C Newton, E R Kay, D A Leigh, W J Buma, A M Brouwer and S Woutersen, Phys Chem Chem Phys, 14, 1865-1875 (2012). Featured on the front cover of Phys Chem Chem Phys issue 6, 14 (2012).

2011

"Strategies and Tactics for the Metal-Directed Synthesis of Rotaxanes, Knots, Catenanes and Higher Order Links", J E Beves, B A Blight, C J Campbell, D A Leigh and R T McBurney, Angew Chem Int Ed, 50, 9260-9327 (2011).
"Active Metal Template Synthesis of a Molecular Trefoil Knot", P E Barran, H L Cole, S M Goldup, D A Leigh, P R McGonigal, M D Symes, J Wu and M Zengerle, Angew Chem Int Ed, 50, 12280-12284 (2011). Featured on the cover of Angewandte Chemie, issue 51, 2011.

[For highlights of this paper see: 'Combining coordination chemistry and catalysis to tie a knot by an active-metal template strategy' C Romuald and F Coutrot, Angew Chem Int Ed, 51, 2544-2545 (2012).]
"A Single Synthetic Small Molecule that Generates Force Against a Load", P Lussis, T Svaldo-Lanero, A Bertocco, C-A Fustin, D A Leigh and A-S Duwez, Nature Nanotech, 6, 553-557 (2011).
[For highlights of this paper see: 'Manmade Molecular Machine Goes To Work' Chem World, 22 Aug 2011; 'Measuring the Force of a Single Synthetic Small Molecule' Nanowerk, 26 Aug 2011; etc.]
"Phosphorus-Based Functional Groups as Hydrogen Bonding Templates for Rotaxane Formation", R Ahmed, A Altieri, D M D'Souza, D A Leigh, K M Mullen, M Papmeyer, A M Z Slawin, J K Y Wong and J D Woollins, J Am Chem Soc, 133, 12304-12310 (2011).
"Sulfur-Containing Amide-Based [2]Rotaxanes and Molecular Shuttles", A Altieri, V Aucagne, R Carrillo, G J Clarkson, D M D'Souza, J A Dunnett, D A Leigh and K M Mullen, Chem Sci, 2, 1922-1928 (2011).
"En Route to a Molecular Sheaf: Active Metal Template Synthesis of a [3]Rotaxane with Two Axles Threaded through One Ring", H M Cheng, D A Leigh, F Maffei, P R McGonigal, A M Z Slawin and J Wu, J Am Chem Soc, 133, 12298-12303 (2011).
"IR Spectroscopy on Jet-Cooled Isolated Two-Station Rotaxanes", A M Rijs, E R Kay, D A Leigh and W J Buma, J Phys Chem A, 115, 9669-9675 (2011).
"Bimodal Dynamics of Mechanically Constrained Hydrogen Bonds Revealed by Vibrational Photon Echoes", P Bodis, S Yeremenko, J Berná, W J Buma, D A Leigh and S Woutersen, J Chem Phys, 134, 134504 (2011).
"Walking Molecules", M von Delius and D A Leigh, Chem Soc Rev, 40, 3656-3676 (2011).
[For a highlight of this paper see: 'Synthetic Strollers', S Everts, Chem & Eng News, 89(12), 43-45 (2011); 'Walking in the nanoworld', M Gross, Chem Ind, 10 Oct 2011, p20-22. Top 10 most highly accessed Chem Soc Rev article March 2011.]
"An AAAA-DDDD Quadruple Hydrogen-Bond Array", B A Blight, C A Hunter, D A Leigh, H McNab and P I T Thomson, Nature Chem, 3, 244-248 (2011).
[For a highlight of this paper see: 'Attractive Arrays', A J Wilson, Nature Chem, 3, 193-194 (2011).]
"Light-Driven Transport of a Molecular Walker in Either Direction along a Molecular Track", M J Barrell, A G Campaña, M von Delius, E M Geertsema and D A Leigh, Angew Chem Int Ed, 50, 285-290 (2011). Featured on the front cover of Angewandte Chemie, issue 1, 2011.

[For highlights of this paper see: 'Synthetic Molecular Bipeds', E. M. Pérez, Angew Chem Int Ed, DOI:10.1002/anie.201006946; 'Walking Molecule Follows The Light', S Everts, Chem & Eng News, 88(43), 44 (2010).]

2010

"Design, Synthesis and Operation of Small Molecules That Walk along Tracks", M von Delius, E M Geertsema, D A Leigh and D-T D Tang, J Am Chem Soc, 132, 16134-16145 (2010).
"Synthesis, Structure, and Dynamic Properties of Hybrid Organic-Inorganic Rotaxanes", B Ballesteros, T B Faust, C-F Lee, D A Leigh, C A Muryn, R G Pritchard, D Schultz, S J Teat, G A Timco and R E P Winpenny, J Am Chem Soc, 132, 15435-15444 (2010).
"Synthesis and Solid State Structure of a Hydrazone-Disulfide Macrocycle and its Dynamic Covalent Ring-Opening Under Acidic and Basic Conditions", M von Delius, E M Geertsema, D A Leigh and A M Z Slawin, Org Biomol Chem, 8, 4617-4624 (2010).
[Selected as an OBC "Hot Article" 2010]
"In Trap Fragmentation and Optical Characterization of Rotaxanes", A M Rijs, I Compagnon, A Silva, J S Hannam, D A Leigh, E R Kay and P Dugourd, Phys Chem Chem Phys, 12, 12556-12561 (2010).
"Interlocked Molecules: Linking Rings Without Templates (N&Vs)", J E Beves and D A Leigh, Nature Chem, 2, 708-710 (2010).
"Ligand-Assisted Nickel-Catalysed sp³-sp³ Homocoupling of Unactivated Alkyl Bromides and its Application to the Active Template Synthesis of Rotaxanes", S M Goldup, D A Leigh, R T McBurney, P R McGonigal and A Plant, Chem Sci, 1, 383-386 (2010).
"Nitrone [2]Rotaxanes: Simultaneous Chemical Protection and Electrochemical Activation of a Functional Group", D M D'Souza, D A Leigh, L Mottier, K M Mullen, F Paolucci, S J Teat and S Zhang, J Am Chem Soc, 132, 9465-9470 (2010).
"Operation Mechanism of a Molecular Machine Revealed Using Time-Resolved Vibrational Spectroscopy", M R Panman, P Bodis, D J Shaw, B H Bakker, A C Newton, E R Kay, A M Brouwer, W J Buma, D A Leigh and S Woutersen, Science, 328, 1255-1258 (2010). Full Article. How it works.
[For highlights of this paper see: 'Molecular machine's movement turns out to be a dishonest gambling game', FOM, 4 June 2010; 'Motion of molecular machinery appears unfair', AllePersberichten (in Dutch), 4 June 2010.]
"Controlled Hydrogen-Bond Breaking in a Rotaxane by Discrete Solvation", A M Rijs, N Sändig, M N Blom, J Oomens, J S Hannam, D A Leigh, F Zerbetto and W J Buma, Angew Chem Int Ed, 49, 3896-3900 (2010).
"An Unusual Nickel−Copper-Mediated Alkyne Homocoupling Reaction for the Active-Template Synthesis of [2]Rotaxanes", J D Crowley, S M Goldup, N D Gowans, D A Leigh, V E Ronaldson and A M Z Slawin, J Am Chem Soc, 132, 6243–6248 (2010).
"Diels-Alder Active-Template Synthesis of Rotaxanes and Metal-Ion-Switchable Molecular Shuttles", J D Crowley, K D Hänni, D A Leigh and A M Z Slawin, J Am Chem Soc, 132, 5309–5314 (2010).
"Sequence Isomerism in [3]Rotaxanes", A-M L Fuller, D A Leigh and P J Lusby, J Am Chem Soc, 132, 4954-4959 (2010).
"Improved Dynamics and Positional Bias with a Second Generation Palladium(II)-Complexed Molecular Shuttle", D A Leigh, P J Lusby, R T McBurney and M D Symes, Chem Commun, 46, 2382-2384 (2010).
"A Synthetic Small Molecule That Can Walk Down a Track", M von Delius, E M Geertsema and D A Leigh, Nature Chem, 2, 96-101 (2010). Full Article. News & Views. How it works. Featured on the front cover of Nature Chemistry issue 2, 2 (2010).

[For highlights of this paper see: 'Tiny Steps (N&Vs)' S Otto, Nature Chem, 2, 75-76 (2010); 'Big Steps for Little Feet', Science, 327, 127 (2010); '"Two-legged" molecular walker takes a stroll' Chem World, 21 Dec 2009; 'Tiny molecular track walker' Chem & Eng News, 87(51), 34 (2009); 'Edinburgh motive force for NEMS' Compute Scotland, 21 Dec 2009. 'Двуногая молекула на (in Russian)' Remedium, 23 Dec 2009. '두 다리로 걷는 보행분자 ('Walking on two legs walking molecule'; in Korean)' GTNET, 23 Dec 2009. 'Tiny molecules walk the track' Science News, 12 Feb 2010. '두 다리로 걷는 보행분자 (in Korean)' HelloDD.com, 12 Feb 2010. '두 다리로 걷는 보행분자 ('Walking on two legs walking molecule'; in Korean)' Radar, 12 Feb 2010. 'Cutting-edge chemistry in 2010' Chemistry World, 21 Dec 2010.]
"Two Axles Threaded Using a Single Template Site: Active Metal Template Macrobicyclic [3]Rotaxanes", S M Goldup, D A Leigh, P R McGonigal, V E Ronaldson and A M Z Slawin, J Am Chem Soc, 132, 315-320 (2010).
[For a highlight of this paper see 'Templated Threading to [3]Rotaxanes' T M Swager and B Esser, Synfacts, 301 (2010)]
"The Application of CuAAC Click Chemistry to Catenane and Rotaxane Synthesis", K D Hänni and D A Leigh, Chem Soc Rev, 39, 1240-1251 (2010).
[Top 10 most highly accessed Chem Soc Rev article April 2010]

2009

"Active Metal Template Synthesis of [2]Catenanes", S M Goldup, D A Leigh, T Long, P R McGonigal, M D Symes and J Wu, J Am Chem Soc, 131, 15924–15929 (2009).
"Photoinduced Shuttling Dynamics of Rotaxanes in Viscous Polymer Solutions", D C Jagesar, S M Fazio, J Taybi, E Eiser, F G Gatti, D A Leigh and A M Brouwer, Adv Funct Mater, 19, 3440-3449 (2009).
"AAA-DDD Triple Hydrogen Bond Complexes", B A Blight, A Camara-Campos, S Djurdjevic, M Kaller, D A Leigh, F M McMillan, H McNab and A M Z Slawin, J Am Chem Soc, 131, 14116-14122 (2009).
"Conformational Flexibility of a Rotaxane Thread Probed by Electronic Spectroscopy in Helium Nanodroplets", S Smolarek, A M Rijs, J S Hannam, D A Leigh, M Drabbels and W J Buma, J Am Chem Soc, 131, 12902-12903 (2009).
"Two-Dimensional Vibrational Spectroscopy of Rotaxane-Based Molecular Machines", P Bodis, M R Panman, B H Bakker, A Mateo-Alonso, M Prato, W J Buma, A M Brouwer, E R Kay, D A Leigh and S Woutersen, Acc Chem Res, 42, 1462-1469 (2009).
"Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide", A Fernandes, A Viterisi, F Coutrot, S Potok, D A Leigh, V Aucagne and S Papot, Angew Chem Int Ed, 48, 6443-6447 (2009); published online as an Angewandte Chemie 'Hot' paper July 27 2009.
"Active Metal Template Synthesis of Rotaxanes, Catenanes and Molecular Shuttles", J D Crowley, S M Goldup, A-L Lee, D A Leigh and R T McBurney, Chem Soc Rev, 38, 1530-1541 (2009).
"Hybrid Organic-Inorganic Rotaxanes and Molecular Shuttles", C-F Lee, D A Leigh, R G Pritchard, D Schultz, S J Teat, G A Timco and R E P Winpenny, Nature, 458, 314-318 (2009). Full Article. Nature Podcast.
[For highlights of this paper see 'The Marriage of Inorganic and Organic Building Blocks for the Assembly of Rotaxanes' E K Brechin and L Cronin, Angew Chem Int Ed, 48, 6948-6949 (2009); 'Rotaxanes go hybrid' Chem & Eng News, 87(12), 11 (2009); 'Major leap for faster computers' BBC News, 19 March 2009; 'Combining nanomagnetics with molecular machines' Compute Scotland, 18 March 2009; 'Scientists make quantum leap in developing faster computers' Nanotechnology Now, 20 March 2009; 'Molecular scale technology used for quantum computers' New Electronics, 19 March 2009; 'Researchers tout molecular-scale devices for quantum computing' EE Times, 20 March 2009; 'Quantum computers moving closer' Singularity & Futurism, 19 March 2009; 'Major breakthrough for quantum computers announced' Daily Debrief, 19 March 2009; 'Major leap for faster computers' Digital Silence, 20 March 2009; 'Critical component of quantum computing discovered' Fudzilla, 22 March 2009; and others]
"Getting Harder: Cobalt(III)-Template Synthesis of Catenanes and Rotaxanes", D A Leigh, P J Lusby, R T McBurney, A Morelli, A M Z Slawin, A R Thomson and D B Walker, J Am Chem Soc, 131, 3762-3771 (2009).
"Stiff and Sticky in the Right Places: Binding Interactions in Isolated Mechanically Interlocked Molecules Probed by Mid-Infrared Spectroscopy", A M Rijs, I Compagnon, J Oomens, J S Hannam, D A Leigh and W J Buma, J Am Chem Soc, 131, 2428-2429 (2009).
"Multistate Photo-Induced Relaxation and Photoisomerization Ability of Fumaramide Threads: A Computational and Experimental Study", P Altoe, N Haraszkiewicz, F G Gatti, P G Wiering, C Frochot, A M Brouwer, G Balkowski, D Shaw, S Woutersen, W J Buma, F Zerbetto, G Orlandi, D A Leigh and M Garavelli, J Am Chem Soc, 131, 104-117 (2009).

2008

"An Ion-Pair Template for Rotaxane Formation and its Exploitation in an Orthogonal Interaction Anion-Switchable Molecular Shuttle", M J Barrell, D A Leigh, P J Lusby and A M Z Slawin, Angew Chem Int Ed, 47, 8036-8039 (2008).
"Tuning Magnetic Properties Using Targeted Structural Distortion: New Additions to a Family of Mn6 Single-Molecule Magnets", L F Jones, M E Cochrane, B D Koivisto, D A Leigh, S P Perlepes, W Wernsdorfer and E K Brechin, Inorg Chim Acta, 361, 3420-3426 (2008).
"Gold(I)-Template Catenane and Rotaxane Synthesis", S M Goldup, D A Leigh, P J Lusby, R T McBurney and A M Z Slawin, Angew Chem Int Ed, 47, 6999-7003 (2008). Featured on the front cover of Angewandte Chemie issue 37, 47 (2008).

['Molecule-of-the-Week' notjustanotherchemblog, 30 August, 2008]
"An Ammonium/bis-ammonium Switchable Molecular Shuttle", D A Leigh and A R Thomson, Tetrahedron, 64, 8411-8416 (2008).
"Cadiot-Chodkiewicz Active Template Synthesis of Rotaxanes and Switchable Molecular Shuttles with Weak Intercomponent Interactions", J Berná, S M Goldup, A-L Lee, D A Leigh, M D Symes, G Teobaldi and F Zerbetto, Angew Chem Int Ed, 47, 4392-4396 (2008).
"Active Template Synthesis of Rotaxanes and Molecular Shuttles with Switchable Dynamics by Four-component Pd(II)-promoted Michael Additions", S M Goldup, D A Leigh, P J Lusby, R T McBurney and A M Z Slawin, Angew Chem Int Ed, 47, 3381-3384 (2008).
"Shaping of a Conformationally Flexible Molecular Structure for Spectroscopy", A M Rijs, B O Crews, M S de Vries, J S Hannam, D A Leigh, M Fanti, F Zerbetto and W J Buma, Angew Chem Int Ed, 47, 3174-3179 (2008).
"Three State Redox-Active Molecular Shuttle That Switches in Solution and on a Surface", G Fioravanti, N Haraszkiewicz, E R Kay, S M Mendoza, C Bruno, M Marcaccio, P G Wiering, F Paolucci, P Rudolf, A M Brouwer and D A Leigh, J Am Chem Soc, 130, 2593-2601 (2008).
[For a highlight of this paper see 'Applied Chemistry Highlights' N P Freestone, Chem & Ind, May 2008, 26-28.]
"A Chemically-Driven Molecular Information Ratchet", M Alvarez-Pérez, S M Goldup, D A Leigh and A M Z Slawin, J Am Chem Soc, 130, 1836-1838 (2008).
[For a highlight of this paper see 'Energy in Motion' D Castelvecchi, Science News, 173(8), 120-121 (2008); 'Free Lunch (at a Cost)' Sci Amer, p 65, May 2009.]
"Beyond Switches: Rotaxane- and Catenane-Based Synthetic Molecular Motors", E R Kay and D A Leigh, Pure Appl Chem, 80, 17-29 (2008).
"Chemically Driven Artificial Molecular Machines", J D Crowley, E R Kay and D A Leigh in Intelligent Materials, M Shahinpoor and H-J Schneider (eds), p. 1-47, RSC, Cambridge (2008).

2007

"Structural Dynamics of Rotaxanes Studied by Infrared Photon Echo Spectroscopy", S Yeremenko, O F A Larsen, P Bodis, W J Buma, J S Hannam, D A Leigh and S Woutersen, Springer Series in Chemical Physics, 88, 430-432 (2007).
"A Switchable Palladium-Complexed Molecular Shuttle and Its Metastable Positional Isomers", J D Crowley, D A Leigh, P J Lusby, R T McBurney, L-E Perret-Aebi, C Petzold, A M Z Slawin and M D Symes, J Am Chem Soc, 129, 15085-15090 (2007).
"A Metal-Complex-Tolerant CuAAC 'Click' Protocol Exemplified through the Preparation of Homo- and Mixed-Metal-Coordinated [2]Rotaxanes", D González Cabrera, B D Koivisto and D A Leigh, Chem Commun, 4218-4220 (2007).
"[2]Rotaxanes through Palladium Active-Template Oxidative Heck Cross-Couplings", J D Crowley, K D Hänni, A-L Lee and D A Leigh, J Am Chem Soc, 129, 12092-12093 (2007).
"Catalytic 'Active-Metal' Template Synthesis of [2]Rotaxanes, [3]Rotaxanes and Molecular Shuttles, and Some Observations on the Mechanism of the Cu(I)-Catalyzed Azide-Alkyne 1,3-Cycloaddition", V Aucagne, J Berná, J D Crowley, S M Goldup, K D Hänni, D A Leigh, P J Lusby, V E Ronaldson, A M Z Slawin, A Viterisi and D B Walker, J Am Chem Soc, 129, 11950-11963 (2007).
"A Catalytic Palladium Active-Metal Template Pathway to [2]Rotaxanes", J Berná, J D Crowley, S M Goldup, K D Hänni, A-L Lee and D A Leigh, Angew Chem Int Ed, 46, 5709-5713 (2007).
[For a highlight of this paper see 'Palladium-Catalyzed Synthesis of Rotaxanes' T M Swager and R M Moslin, Synfacts, 11, 1158 (2007).]
"Heterovibrational Interactions, Cooperative Hydrogen Bonding and Vibrational Energy Relaxation Pathways in a Rotaxane", P Bodis, R Timmer, S Yeremenko, W J Buma, J S Hannam, D A Leigh and S Woutersen, J Phys Chem C, 111, 6798-6804 (2007).
"The Effect of Solvent Upon Molecularly Thin Rotaxane Film Formation", A A Farrell, E R Kay, G Bottari, D A Leigh and S P Jarvis, Appl Surf Sci, 253, 6090-6095 (2007).
"One Template, Multiple Rings: Controlled Iterative Addition of Macrocycles onto a Single Binding Site Rotaxane Thread", A-M L Fuller, D A Leigh and P J Lusby, Angew Chem Int Ed, 46, 5015-5019 (2007); published online as an Angewandte Chemie 'VIP' paper May 25 2007.
"A Rotaxane Mimic of the Photoactive Yellow Protein Chromophore Environment: Effects of Hydrogen Bonding and Mechanical Interlocking on a Coumaric Amide Derivative", J Berná, A M Brouwer, S M Fazio, N Haraszkiewicz, D A Leigh and C M Lennon (neé Keaveney), Chem Commun, 1910-1912 (2007).
"Coumaric Amide Rotaxanes: Effects of Hydrogen Bonding and Mechanical Interlocking on the Photochemistry and Photophysics", A M Brouwer, S M Fazio, N Haraszkiewicz, D A Leigh and C M Lennon (neé Keaveney), Photochem. Photobiol. Sci., 6, 480-486 (2007).
"A Molecular Information Ratchet", V Serreli, C-F Lee, E R Kay and D A Leigh, Nature, 445, 523-527 (2007). Full Article. Making the Paper. Nature Nanotech N&V's. How it Works.
[Forhighlights of this paper see 'Knowledge is power!'(N&V's) A P Davis, Nature Nanotech, 2, 135-136 (2007); ‘A demon ofa device’ Nature (news), 31 Jan2007; ‘Molecular machines: Facing theirdemons’ Nature Nanotech, 2 Feb2007; ‘Maxwell’s demon tamed’ Physicsweb, 31 Jan 2007; ‘Demon ratchets up nanotech revolution’ Chemistry World, 31 Jan 2007; ‘Cutting-edge chemistry in 2007’ Chemistry World, 18 Dec 2007; ‘Scientists build nanomachine envisaged 150years ago’ Scientific American,31 Jan 2007; ‘Demonic chemistry’ Intute, 2 Feb 2007; ‘Tiny engine boosts nanotech hopes’ BBC news, 1 Feb 2007; ‘1867 nanomachine now reality’ CNN, 2 Feb 2007; ‘Laws of Nature survive attack by Nano Demon’ Daily Telegraph, 2 Feb 2007; 'Opening the door to Maxwell's Demons' The Scotsman, 3 Feb 2007;‘Maxwell’sdevilishly clever idea moves closer to reality’ The Herald, 1 Feb 2007; ‘Scientists build nanomachine envisaged 150years ago’ Washington Post, 31Jan 2007; ‘Reviving a 19^thcentury nanomachine’ The Australian,1 Feb 2007; ‘Scientists build Maxwell’sdemon’ Daily News (India), 1 Feb2007; ‘Nanomachines: Maxwell’s Demonbecomes a reality’ Xinhua News(China), 1 Feb 2007; ‘Scientiststake 150 years to build nanomachine’ MacUser,1 Feb 2007; ‘150-year-old idea inspiresnanomachine’ MSNBC, 31 Jan 2007;‘A fundamentally new type ofmotor-mechanism for artificial nanomachines’ Nanowerk News, 31 Jan 2007; ‘Maxwell’sDemon Created by Scottish Scientists’ Zpenergy,1 Feb 2007; ‘Edinburgh scientists craftmicroscopic nanomachines’ engadget,1 Feb 2007; ‘Chemists take 150 years tobuild nanomotor’ ABC news, 1 Feb2007; ‘140 years later, James ClerkMaxwell’s ‘demon’ materializes’ SooToday,1 Feb 2007; ‘Un nanomotore permicromacchine il diavoletto di Maxwell diventa realtá’ (in Italian) La Repubblica, 1 Feb 2007; ‘Gesetzestreue Dämonen’ (in German) Telepolis, 1 Feb 2007; ‘Maxwellsmoleculaire duveltje’ (in Dutch) C2W,1 Feb 2007; ‘Демон позапрошлого веканарушил равновесие круглых молекул’(in Russian) Membrana, 2 Feb 2007; ‘现代版麦克斯韦“思想实验” ’(in Chinese) Nature Asia-Pacific, 1Feb 2007; 'El tridente informativo del demonio de Maxwell ' (in Spanish) Anales de Química, 103, 74, (2007);‘Cientificos Construyen Primer Motor Basado En NanoTecnologia’ (in Spanish) Terra, 5 Feb2007; ‘La Diabolica Nanomacchina del Signor Maxwell’ (in Italian) Next Station, 4 Feb2007; ‘Dalla Scozia il Micromotore che Muovera le Nanomacchine’ (in Italian) La Stampa, 1 Feb2007; ‘Cientistas dão mais um passo em pesquisas da nanotecnologia’ (in Portuguese) swissinfo, 9 Feb2007; and others ]
"Amide-based molecular shuttles (2001-2006)", J Berná, G Bottari, D A Leigh and E M Pérez, Pure Appl. Chem., 79, 39-54 (2007).
"Extremely Strong and Readily Accessible AAA-DDD Triple Hydrogen Bond Complexes", S Djurdjevic, D A Leigh, H McNab, S Parsons, G Teobaldi and F Zerbetto, J Am Chem Soc, 129, 476-477 (2007).
[For a highlight of this paper see 'Really Strong Triple H-Bonding', Chem & Eng News, 85(2), 44 (2007).]
"Synthetic Molecular Motors and Mechanical Machines", E R Kay, D A Leigh and F Zerbetto, Angew Chem Int Ed, 46, 72-191 (2007).
[Most-accessed 2007 Angewandte Chemie article Dec 2006-Nov 2007; Most-cited 2007 Angewandte Chemie article as of 9 March 2009 (source: Angewandte Chemie)]

2006

"Self-organization of Nano-lines and Dots Triggered by a Local Mechanical Stimulus", F Biscarini, M Cavallini, R Kshirsagar, G Bottari, D A Leigh, S León and F Zerbetto, Proc Natl Acad Sci USA, 103, 17650-17654 (2006).
[For a highlight of this paper see 'Self-assembly: Push to organize', A LChun, Nature Nanotech, 2, 15 (2007)]
"Switchable Dual Binding Mode Molecular Shuttle", D A Leigh and A R Thomson, Org Lett, 8, 5377-5379 (2006).
"Adsorption of Fumaramide [2]rotaxane and its Components on a Solid Substrate: A Coverage-dependent Study", C M Whelan, F G Gatti, D A Leigh, S Rapino, F Zerbetto and P Rudolf, J Phys Chem B, 110, 17076-17081 (2006).
"Chemoselective Formation of Successive Triazole Linkages in One Pot: 'Click-Click' Chemistry", V Aucagne and D A Leigh, Org Lett, 8, 4505-4507 (2006).
[Top-ten most-requested Chemistry journal article on SciFinder/SciFinder Scholar/STN/ChemAbs in 4th quarter 2006, CAS Science Spotlight]
"Surface Enhanced Second Harmonic Generation from Macrocycle, Catenane and Rotaxane Thin Films: Experiments and Theory", I Arfaoui, V Bermúdez, G Bottari, C De Nadai, J-P Jalkanen, F Kajzar, D A Leigh, M Lubomska, S M Mendoza, J Niziol, P Rudolf and F Zerbetto, J Phys Chem B, 110, 7648-7652 (2006).
"Lighting Up Nanomachines", E R Kay and D A Leigh, Nature, 440, 286-287 (2006).
"Dynamic Chirality: Molecular Shuttles and Motors", D A Leigh and E M Pérez, in Supramolecular Chirality, M Crego-Calama & D N Reinhoudt (eds.), Topics Curr Chem, 265, 185-208 (2006).
"Beyond Switches: Ratcheting a Particle Energetically Uphill with a Compartmentalized Molecular Machine", M N Chatterjee, E R Kay and D A Leigh, J Am Chem Soc, 128, 4058-4073 (2006).
[15th most-cited J Am Chem Soc article in 2006]
"Catalytic "Click" Rotaxanes: A Substoichiometric Metal-Template Pathway to Mechanically Interlocked Architectures", V Aucagne, K D Hänni, D A Leigh, P J Lusby and D B Walker, J Am Chem Soc, 128, 2186-2187 (2006).
"An Allosterically Regulated Molecular Shuttle", D S Marlin, D González Cabrera, D A Leigh and A M Z Slawin, Angew Chem Int Ed, 45, 1385-1390 (2006).
"Rotaxanes of Cyclic Peptides", V Aucagne, D A Leigh, J S Lock and A R Thomson, J Am Chem Soc, 128, 1784-1785 (2006).
[For highlights of this paper see: ' Peptides Trapped On A Thread', Chem & Eng News, Jan 25 (2006)]
"Self-organization of Rotaxane Thin Films into Spatially Correlated Nanostructures: Morphological and Structural Aspects", J-F Moulin, J C Kengne, R Kshirsagar, M Cavallini, F Biscarini, S León, F Zerbetto, G Bottari and D A Leigh, J Am Chem Soc, 128, 526-532 (2006).
"Complexation-Induced Translational Isomerism: Shuttling through Stepwise Competitive Binding", D S Marlin, D González Cabrera, D A Leigh and A M Z Slawin, Angew Chem Int Ed, 45, 77-83 (2006).

2005

"Hydrogen Bond-Assembled Synthetic Molecular Motors and Machines", E R Kay and D A Leigh, in Molecular Machines, T R Kelly (ed.), Topics Curr Chem, 262, 133-177 (2005).
"Experimental and Theoretical Study of the Adsorption of Fumaramide [2]Rotaxane on Au(111)and Ag(111) Surfaces", S M Mendoza, C M Whelan, J-P Jalkanen, F Zerbetto, F G Gatti, E R Kay, D A Leigh, M Lubomska and P Rudolf, J Chem Phys, 123, 244708 (2005).
"Conservative and Dissipative Force Imaging of Switchable Rotaxanes with Frequency-modulation Atomic Force Microscopy", A A Farrell, T Fukuma, T Uchihashi, E R Kay, G Bottari, D A Leigh, H Yamada and S P Jarvis, Phys. Rev. B, 72, 125430 (2005).
"Half-rotation in a [2]Catenane via Interconvertible Pd(II) Coordination Modes", D A Leigh, P J Lusby, A M Z Slawin and D B Walker, Chem. Commun., 4919-4921 (2005).
"Probing the Structure of a Rotaxane with Two-dimensional Infrared Spectroscopy", O F A Larsen, P Bodis, W J Buma, J S Hannam, D A Leigh and S Woutersen, Proc Natl Acad Sci USA, 102, 13378-13382 (2005).
[For highlights of this paper see: 'Fast Vibrational Coupling', Science, 309, 1967 (2005); 'Coherent femtosecond multidimensional probes of molecular vibrations', S Mukamel and W Zhuang, PNAS, 102, 13717-13718 (2005); 'Observing a rotaxane twist and bend', PNAS, 102, 13353 (2005); 'Moleculaire motortjes geflitst' (in Dutch), Chemisch2Weekblad, 5th September (2005); 'Moleculaire machines geflitst' (in Dutch), Kennislink, 6th September (2005).]
"Macroscopic Transport by Synthetic Molecular Machines", J Berná, D A Leigh, M Lubomska, S M Mendoza, E M Pérez, P Rudolf, G Teobaldi and F Zerbetto, Nature Mater, 4, 704-710 (2005). Full article. Movie 1. Movie 2. Movie 3. How does it work?
[For highlights of this paper see: 'Drop in attendance at motor show', D Fitzmaurice Nature Mater, 4, 657 (2005); 'Drop by drop', Nature, 437, 4-5 (2005); 'Liquid drop takes big nano step', BBC news, 7th September 2005; 'Scientists develop molecule machine' The Guardian, 8th September 2005; 'Nanomachines' represent huge stride in technology' Financial Times, 8th September 2005; 'Small motor, huge power' The Times, 8th September 2005; 'Nanotech team move water droplets' BBC news, 29 August 2005; 'Good Morning Scotland', BBC Radio Scotland, 29 August 2005; 'Molecular motors push liquid uphill', New Scientist, 29 August 2005; 'Scientists take the effort out of moving objects', The Herald, 29 August 2005; 'Lasers used to move water', Metro, 30 August 2005; 'Forscher lassen Flüssigkeit bergauf fließen' (in German), Netzeitung Wissenschaft, 29 August 2005; 'La nanotecnología da un “enorme” paso de un milímetro' (in Spanish), El Pais, 08 September 2005; 'Las 'nanomáquinas' terapéuticas' (in Spanish), El mundo, 08 September 2005; 'Petit et Costaud!' (in French), Le Point, 08 September 2005; 'Druppel tart zwaartekracht dankzij moleculaire motoren' (in Dutch), Kennislink, 2005; ‘분자 모터로 액체를 밀어 올린다’ (in Korean), Science Donga, October issue 2005; ‘Máquinas moleculares sintéticas capaces de transportar objetosmacroscópicos’ (in Spanish), Anales de Química, 101(3), 80 2005; and others.]
Who dugg this science?
"Selecting Topology and Connectivity through Metal-Directed Macrocyclization Reactions: A Square Planar Palladium [2]Catenate and Two Noninterlocked Isomers", A-M L Fuller, D A Leigh, P J Lusby, A M Z Slawin and D B Walker, J. Am. Chem. Soc, 127, 12612-12619 (2005).
"Rare and Diverse Binding Modes Introduced through Mechanical Bonding", D A Leigh, P J Lusby, A M Z Slawin and D B Walker, Angew. Chem. Int. Ed., 44, 4557-4564 (2005).
"Patterning through Controlled Submolecular Motion: Rotaxane-Based Switches and Logic Gates that Function in Solution and Polymer Films", D A Leigh, M Á F Morales, E M Pérez, J K Y Wong, C G Saiz, A M Z Slawin, A J Carmichael, D M Haddleton, A M Brouwer, W J Buma, G W H Wurpel, S León and F Zerbetto, Angew. Chem. Int. Ed., 44, 3062-3067 (2005). Featured on the front cover of Angewandte Chemie issue 20, 44 (2005).

[For highlights of this paper see 'Molecular Memories Start to Gel', Materials Update, 26 May 2005; 'Switches Based on Submolecular Movement', Materials Today, July/August 2005, page 21.]
"Synthetic Molecular Machines", E R Kay and D A Leigh in ‘Functional Artificial Receptors’, T Schrader, A D Hamilton (eds.), Wiley-VCH, Weinheim, pp 333-406 (2005).
"IRAS investigation of a Catenane Adsorption on Au(111)", C A Fustin, S Haq, A Wingen, C Grégoire, R Raval, P Dumas, J S Hannam, D A Leigh and P Rudolf, Surf Sci, 580, 57-62 (2005).

2004

"A Reversible Synthetic Rotary Molecular Motor", J V Hernandez, E R Kay and D A Leigh, Science, 306, 1532-1537 (2004). Full Article. How does it work?
[For highlights of this paper see Financial Times (London), 26 November 2004, BBC Radio Scotland 29 November 2004, BBC1 'Reporting Scotland' 30th November 2004, 'First two-way artificial molecular motor obeys the laws of thermodynamics', Chemistry World, January 2005, 'Molecular motor goes both ways', Technology Research News, January 2005, 'A Reversible Synthetic Rotary Molecular Motor', Plausible Futures Newsletter, 30th November 2004, 'Molecular Motors - Naturally' Global Nanotechnology - The where, the when and the why, 30 November 2004, 'Submolekularer Elektronenmotor auf [2]Catenangrund' (in German), Chem. Unserer Zeit, 39, 230-235 (2005); and others.]
"Structural, Electrochemical, and Photophysical Properties of a Molecular Shuttle Attached to an Acid- Terminated Self-Assembled Monolayer", F Cecchet, P Rudolf, S Rapino, M Margotti, F Paolucci, J Baggerman, A M Brouwer, E R Kay, J K Y Wong and D A Leigh, J. Phys. Chem. B, 108, 15192-15199 (2004).
"Shuttling Through Reversible Covalent Chemistry", D A Leigh andE M Pérez, Chem. Commun., 2262-2263 (2004). [One of the top ten accessed Chem. Comm. articles for October 2004]
"Mechanically Linked Poly(ethylene terephthalate)", C A Fustin, G JClarkson, D A Leigh, F Van Hoof, A M Jonas, and C Bailly, Macromolecules, 37, 7884-7892 (2004).
"The Mechanism of Formation of Amide-Based Interlocked Compounds:Prediction of a New Rotaxane-Forming Motif", D A Leigh, A Venturini, A J Wilson, J K Y Wong and F Zerbetto, Chem. Eur. J, 10, 4960-4969 (2004).
"A Generic Basis for Some Simple Light-Operated Mechanical MolecularMachines", E M Pérez, D T F Dryden, D A Leigh, G Teobaldi and F Zerbetto, J. Am. Chem. Soc, 126, 12210-12211 (2004).
"A 3D Interlocked Structure from a 2D Template: Structural Requirementsfor the Assembly of a Square-Planar Metal-Coordinated [2]Rotaxane", A-M Fuller, D A Leigh, P J Lusby, I D H Oswald, S Parsons and D B Walker, Angew. Chem. Int. Ed., 43, 3914-3918 (2004).
"Controlled Submolecular Translational Motion in Synthesis: A MechanicallyInterlocking Auxiliary", J S Hannam, S M Lacy, D A Leigh, C G Saiz, A M Z Slawin and S G Stitchell, Angew. Chem. Int. Ed., 43, 3260-3264 (2004).

[For highlights of this paper see: 'Mechanical Synthesis', Science, 305, 149 (2004) and others]
"Shuttling through Anion Recognition", C M Keaveney and D A Leigh, Angew. Chem. Int. Ed., 43, 1222-1224 (2004).
"A Simple General Ligand System for Assembling Octahedral Metal-Rotaxane Complexes", L Hogg, D A Leigh, P J Lusby, A Morelli, S Parsons and J K Y Wong, Angew. Chem. Int. Ed., 43, 1218-1221 (2004); published on-line as an Angewandte Chemie'VIP' paper 27 January 2004.
"Optical and Low Frequency Electric Field Testing of the Mobility of Mobile Parts in Catenanes and Rotaxanes", K Nowicka, P A Chollet, F Kajzar, G Bottari, F G Gatti, D A Leigh and A Miniewicz, Nonlinear Optics, Quant. Optics, 32, 175-186 (2004).
"Solution and Solid-State Properties of Mechanically LinkedPolycarbonates", C A Fustin, C Bailly, G J Clarkson, T H Galow and D A Leigh, Macromolecules, 37, 66-70 (2004).

2003

"Summing Up Ligand Binding Interactions", D A Leigh, Chem & Biol, 10, 1143-1144 (2003).

"Entropy-Driven Translational Isomerism: A Tristable Molecular Shuttle", G Bottari, F Dehez, D A Leigh, P J Nash, E M Pérez, J K Y Wong and F Zerbetto, Angew. Chem. Int. Ed., 42, 5886-5889 (2003).

"Chiroptical Switching in a Bistable Molecular Shuttle", G Bottari, D A Leigh, and E M Pérez, J. Am. Chem. Soc., 125, 13360-13361 (2003).

"Grafting of Benzylic Amide Macrocycles onto Acid-Terminated Self-Assembled Monolayers Studied by XPS, RAIRS, and Contact Angle Measurements", F Cecchet, M Pilling, L Hevesi, S Schergna, J K Y Wong, G J Clarkson, D A Leigh and P Rudolf, J. Phys. Chem. B, 107, 10863-10872 (2003).

"Photoinduced Dynamics in Hydrogen-Bonded Rotaxanes", A M Brouwer, S M Fazio, C Frochot, F G Gatti, D A Leigh, J K Y Wong and G W H Wurpel, Pure Appl. Chem., 75, 1055-1060 (2003).

"Unidirectional Rotation in a Mechanically Interlocked Molecular Rotor", D A Leigh, J K Y Wong, F Dehez and F Zerbetto, Nature, 424, 174-179 (2003). Full Article. How does it work?

[For highlights of this paper see: “Chemistry in motion – unidirectional rotating molecular motors”, Angew. Chem. Int. Ed., 35, 1622-1624 (2004); “Chemical Highlights of 2003”, Chem. & Eng. News, 81(51), 39-50 (2003); “Chemical turnstiles”, Science, 301, 438-439 (2003); “Molecular motor has novel three-ring design”, Chem. & Eng. News, 81(28), 14 (2003); “Nano-motors sent round the bend”, Financial Times (London), 11 July 2003; "Forget fiction: nano-motors are here" Daily Telegraph, 13 August 2003; and others.]

"Electrochemically Switchable Hydrogen-Bonded Molecular Shuttles", A Altieri, F G Gatti, E R Kay, D A Leigh, D Martel, F Paolucci, A M Z Slawin and J K Y Wong, J. Am. Chem. Soc., 125, 8644-8654 (2003).
"Rotaxane Building Blocks bearing Blocked Isocyanate Stoppers - Polyrotaxanes through Post-Assembly Chain Extension", T J Kidd, T J A Loontjens, D A Leigh and J K Y Wong, Angew. Chem. Int. Ed., 42, 3379-3383 (2003); published on-line as an Angewandte Chemie 'VIP' paper 3 July 2003.
"Molecules in Motion: Towards Hydrogen Bond-Assembled Molecular Machines", D A Leigh in 'Organic Nanophotonics' F Charra, V M Agranovich and F Kajzar (eds.), p. 47-56, Kluwer, Dordrecht, (2003).
"Synthesis and Characterization of Mechanically-linked Polycarbonates", C-A Fustin, C Bailly, G J Clarkson, P De Groote, T H Galow, D A Leigh, D Robertson, A M Z Slawin and J K Y Wong, Polymer Preprints, 44, 758-759 (2003).
"Remarkable Positional Discrimination in Bistable Light- and Heat- Switchable Hydrogen-Bonded Molecular Shuttles", A Altieri, G Bottari, F Dehez, D A Leigh, J K Y Wong and F Zerbetto, Angew. Chem. Int. Ed., 42, 2296-2300 (2003); published on-line as an Angewandte Chemie 'Hot' paper 13 May 2003.
"'Magic Rod' Rotaxanes: The Hydrogen Bond-Directed Synthesis of Molecular Shuttles under Thermodynamic Control", J S Hannam, T J Kidd, D A Leigh and A J Wilson, Org. Lett., 5, 1907-1910 (2003).
"A Hydrogen Bond-Assembled Fullerene Molecular Shuttle", T Da Ros, D M Guldi, A Farran Morales, D A Leigh, M Prato and R Turco, Org. Lett., 5, 689-691 (2003).
"Rotaxanes - novel photonic molecules", V Bermudez, T Gase, F Kajzar, N Capron, F Zerbetto, F G Gatti, D A Leigh and S Zhang, Opt Mater, 21, 39-44 (2003).
"Mechanically Linked Polycarbonate", C A Fustin, C Bailly, G J Clarkson, P De Groote, T H Galow, D A Leigh, D Robertson, A M Z Slawin and J K Y Wong, J. Am. Chem. Soc., 125, 2200-2207 (2003).
"Information Storage using Supramolecular Surface Patterns" M Cavallini, F Biscarini, S León, F Zerbetto, G Bottari and D A Leigh, Science, 299, 531 (2003). Full Article

[For highlights of this paper see: "Molecular abacus stores abundant information” Scientific American, Jan 27, 2003; “Molecular dots rise for information storage” Institute of Physics News, 27 Jan, 2003; “Molecular abacus” Materials Today, March 2003; “Bumpy surface stores data” Technology Research News, 29 Jan 2003; “DIY molecules” The Engineer, 7 Feb 2003; “Intelligent molecules on the way”, The Herald, March 31, 2003; “La molecola intelligente manda in pensione il dvd”, La Repubblica, 24 Jan 2003; “Intelligent molecules for more efficient DVD’s”, Reuters, 29 Jan 2003 etc.]

"Photoisomerization of a Rotaxane Hydrogen Bonding Template: Light-Induced Acceleration of a Large Amplitude Rotational Motion" F G Gatti, S Leòn, J K Y Wong, G Bottari, A Altieri, M A Farran Morales, S J Teat, C Frochot, D A Leigh, A M Brouwer and F Zerbetto, Proc. Natl. Acad. Sci. USA, 100, 10-14 (2003).

[For highlights of this paper see: "Nanowheels Get Revved Up", ScienceNow, 23 December 2002; and "Micro-machines can get boost from UV rays", UPI ScienceNews, 24 December 2002.]

2002

"From Reactants to Products via Simple Hydrogen-Bonding Networks: Information Transmission in Chemical Reactions" G Brancato, F Coutrot, D A Leigh, A Murphy, J K Y Wong and F Zerbetto, Proc. Natl. Acad. Sci. USA, 99, 4967-4971 (2002).

"Switching "On" and "Off" the Expression of Chirality in Peptide Rotaxanes" M Asakawa, G Brancato, M Fanti, D A Leigh, T Shimizu, A M Z Slawin, J K Y Wong, F Zerbetto, and S Zhang, J. Am. Chem. Soc., 124, 2939-2950 (2002).

"The Effect of Mechanical Interlocking on Crystal Packing: Predictions and Testing"F Biscarini, M Cavallini, D A Leigh, S León, S J Teat, J K Y Wong, F Zerbetto, J. Am. Chem. Soc., 124, 225-233 (2002).

"Procedure for the Storage of Information at Extremely High Density on Thin Films of Bistable Molecules", F. Biscarini, M. Cavallini, D. A. Leigh and F. Zerbetto, Patent application No. BO2002/12/4, 4th Dec 2002.

"Light-Induced Changes in NO₂-Substituted Rotaxanes: Switching Behavior in a Mechanically Interlocked Architecture" V Bermudez, P A Chollet, F Kajzar, A Lorin, G Bottari, F G Gatti and D A Leigh, Mol. Cryst. Liquid Cryst., 374 , 343-356 (2002).

"Spontaneous Fabrication of Microscopic Arrays of Molecular Structures with Submicron Length Scales " M Cavallini, F Biscarini, M Massi, A Farran Morales, D A Leigh and F Zerbetto, Nano Lett., 2, 635-639 (2002).

"Effect of Potassium Intercalation on the Electronic and Vibrational Properties of Benzylic Amide [2]Catenane Films" C A Fustin, R Gouttebaron, R Caudano, P Rudolf, D A Leigh, M Fanti, A Krug and F Zerbetto, Surf. Sci., 515, 45-52 (2002).

"The Effect of Guest Inclusion on the Crystal Packing of p-tert-butylcalix-4-arenes " S Leòn, D A Leigh and F Zerbetto, Chem. Eur. J., 8, 4854-4866 (2002).

"Solid-State Fingerprints of Molecular Threading Detected by Inelastic Neutron Scattering" G Bottari, R Caciuffo, M Fanti, D A Leigh, S F Parker and F Zerbetto, ChemPhysChem, 1038-1041 (2002).

"Excited and Ionic States of Formamide: An Excited-state Photoelectron Spectroscopy and ab initio Study" D H A ter Steege, C Lagrost, W J Buma, D A Leigh and F Zerbetto, J. Chem. Phys., 117, 8270-8280 (2002).

"Adsorption of a Benzylic Amide Macrocycle on a Solid Substance: XPS and HREELS Characterization of Thin Films Grown on Au(III)" C M Whelan, F Cecchet, R Baxter, F Zerbetto, G J Clarkson, D A Leigh and P Rudolf, J. Chem. Phys. B, 106, 8739-8746 (2002).

2001

"Make me a Molecule" S E Gibson, K J Hale, D A Leigh, N K Terrett, J Williams in "CuttingEdge Chemistry", Ed. T. Lister, S. Aldridge, J. Johnstone and C. Osborne,pp 15-32, RSC, Cambridge (2001).

"Enhanced Hydrogen Bonding Induced by Optical Excitation: Unexpected Subnanosecond Photoinduced Dynamics in a Peptide- based [2]Rotaxane" G W H Wurpel, A M Brouwer, I H M van Stokkum, A Farran and D A Leigh J. Am. Chem. Soc., 123, 11327-11328(2001).

[Other output] "Jennifer Leigh, 6 lbs, 0oz" S Y Leigh, D A Leigh, Nature (Biology), 3rd July (2001). Supplementary Information.

"Mechanically-Linked Macromolecules" G J Clarkson & D A Leigh in "Emerging Themes in Polymer Science", Ed. A J Ryan, Royal Society of Chemistry, Cambridge, pp 299-306 (2001)

"Stiff, and Sticky in the Right Places: The Dramatic Influence of Preorganizing Guest Binding Sites on the Hydrogen Bond-Directed Assembly of Rotaxanes", F G Gatti, D A Leigh, S A Nepogodiev, A M Z Slawin, S J Teat,J K Y Wong, J. Am. Chem. Soc., 123, 5983-5989 (2001).

"Benzylic Imine Catenates: Readily Accessible Octahedral Analogues of the Sauvage Catenates" D A Leigh, P J Lusby, S J Teat, A J Wilson, J K Y Wong, Angew. Chem. Int. Ed., 40, 1538-1543 (2001)

"Photoinduction of Fast, Reversible Translational Motion in a Hydrogen-Bonded Molecular Shuttle" A M Brouwer, C Frochot, F G Gatti, D A Leigh,L Mottier, F Paolucci, S Roffia, G W H Wurpel, Science , 291 , 2124-2128 (2001). Full Article. Animation.

[For a highlight of this article see: "A Light-Driven Linear Motor at the Molecular Level", Jean-Pierre Sauvage, Science, 291 , 2105-2106 (2001)]

"The Inelastic Neutron Scattering of Two Benzylic Amide [2]Catenanes" D A Leigh, S F Parker, D Timpel, F Zerbetto, J. Chem. Phys. , 114 , 5006-5011 (2001)

"Quantum-Mechanical Description of Macrocyclic Ring Rotation in Benzylic Amide [2]Catenanes", D A Leigh, A Troisi, F Zerbetto, Chem. Eur. J. , 7, 1450-1454 (2001)

"Conformational self-recognition as the origin of dewetting in bistable molecular surfaces", M Cavallini, R Lazzaroni, R Zamboni, F Biscarini, D Timpel, F Zerbetto, G J Clarkson and D A Leigh, J Phys Chem B., 105, 10826-10830 (2001)

"Photoemission Study of Pristine and Potassium Intercalated Benzylic Amide [2]Catenane Films", C-A Fustin, R Gouttebaron, C De Nadaï, R Caudano, P Rudolf, F Zerbetto and D A Leigh, Surface Science, 474, 37-40 (2001)

"A High Resolution Electron Energy Loss Spectroscopy Study of the Adsorption of a Benzylic Amide Macrocycle on Au(111)" C M Whelan, F Cecchet, G J Clarkson, D A Leigh, R Caudano and P Rudolf, SurfaceScience, 474, 71-80 (2001).

"Solid-state optical properties of the methyl-exopyridine-anthracene rotaxane" GGadret, R Zamboni, P Schouwink, R F Mahrt, J Thies, T Loontjens, and D A Leigh, Chem Phys., 269, 381-388 (2001).

"Optical and electroemission properties of thin films of anthracene-based rotaxanes", G Gadret, G Ruani, M Cavallini, F Biscarini, M Murgia, R Zamboni, G Giro, M Cocchi, V Fattori, T Loontjens, J Thies, D A Leigh, A F Morales and R F Mahrt, Appl Surf Sci., 175, 369-373 (2001).

"Photophysical properties of thin films and solid phase of switchable anthracene-basedrotaxanes", G Giro, M Cocchi, V Fattori, G Gadret, G Ruani, M Cavallini,F Biscarini, R Zamboni, T Loontjens, J Thies, D A Leigh, A F Morales and R F Mahrt, Synthetic Metals, 122, 63-65 (2001).

"Excimer-like electroluminescence from thin films of switchable anthracene-based rotaxanes", G Giro, M Cocchi, V Fattori, G Gadret, G Ruani, M Murgia, M Cavallini, F Biscarini, R Zamboni, T Loontjens, J Thies, D A Leigh and A F Morales, Synthetic Metals, 122, 27-29 (2001).

2000

"Influencing Intramolecular Motion with an Alternating Electric Field", V Bermudez, N Capron, T Gase, F G Gatti, F Kajzar, D A Leigh, F Zerbetto and S Zhang, Nature, 406, 608-611(2000).

[For a highlights of this paper see: “Electric Field Powers Molecular Carousel”, Chem & Eng News, and numerous other publications, August 14, 32 (2000).]

"Reducing Molecular Shuttling to a Single Dimension", D A Leigh, A Troisi and F Zerbetto, Angew Chem Int Ed, 39, 350-353 (2000).

"Physical Consequences of a Mechanically Interlocked Architecture: Benzylic Amide Catenane NH Stretching Vibrations as Sensitive Probes for Weakly Hydrogen-Bonding Environments" C-A Fustin, D A Leigh, P Rudolf, D Timpel and F Zerbetto, ChemPhysChem, 97-100 (2000).

"Oligomeric and Polymeric Catenanes" D A Leigh and R A Smith in "Cyclic Polymers" (2nd Edition), J A Semlyen (Ed), 561-600, Kluwer, Dordrecht (2000).

"Self-assembly of Mechanically Interlocked and Threaded Rings: a HREELS and XPS Study of Thiol-functionalised Catenane and Rotaxane Molecules on Au(111)",C De Nadai, C M Whelan, C Perollier, G Clarkson, D A Leigh, R Caudano and P Rudolf, Surf. Sci., 454-456 , 112-117 (2000).

"Nonlinear optical properties of benzylic amide [2] catenanes: a novel versatile photonic material", D Grando, T Gase, F Kajzar, M Fanti, F Zerbetto, A Murphy and D A Leigh Mol. Crys. Liq. Crys., 353,545-559 (2000).

1999

""Smart" Rotaxanes: Shape Memory and Control in Tertiary Amide Peptido[2]rotaxanes ", W Clegg, C Gimenez-Saiz, D A Leigh, A Murphy, A M Z Slawin and S J Teat, J Am Chem Soc, 121, 4124-4129 (1999).

"Make me a Molecule ", S E Gibson, K J Hale, D A Leigh, N K Terrett and J Williams in "The Age of the Molecule" Ed. N Hall, pp 13-44, RSC, Cambridge, (1999).

"How do Benzylic Amide [2]Catenane Rings Rotate?", M S Deleuze, D A Leigh and F Zerbetto, J Am Chem Soc, 121, 2364-2379 (1999).

"Molecular Tailoring: The Made-to-Measure Properties of Rotaxanes", D A Leigh and A Murphy, Chem Ind, 178-183 (1999).

[Front cover “Stitched to Order: Rotaxanes offer Bespoke Molecules”, Chem & Ind, issue 5, 1 March 1999.]

"Organic "Magic Rings" - The Hydrogen Bond-Directed Assembly of Catenanes Under Thermodynamic Control", T J Kidd, D A Leigh and A J Wilson, J Am Chem Soc, 121, 1599-1600 (1999).

"Electrochemically Induced Dynamics of a Benzylic Amide [2]Catenane", P Ceroni, D A Leigh,L Mottier, F Paolucci, S Roffia, D Tetard and F Zerbetto, J Phys Chem B, 103, 10171-10179 (1999).

"Linear and Unanticipated Second-Order Nonlinear Optical Properties of Benzylic Amide [2]Catenane Thin Films: Evidence of Partial Rotation of the Interlocked Molecular Rings in the Solid State", T Gase, D Grando, P-A Chollet, F Kajzar, A Murphy and D A Leigh, Adv Mater, 11, 1303-1306 (1999).

"STM Investigation ofFlexible Supramolecules: Benzylic Amide [2]Catenanes", F Biscarini,W Gebauer, D DiDomenico, R Zamboni, J I Pascual, D A Leigh, A Murphyand D Tetard, Synthetic Metals, 102,1466-1467 (1999).

"Raman and Far Infrared Characterization of the Simplest Benzylic Amide [2]Catenane ", R Zamboni, M Muccini, W Gebauer, F Biscarini, M Murgia, G Ruani, D A Leigh, A Murphy and D Tetard, Synthetic Metals, 102, 1556-1557 (1999).

1998

"From Catenanes to Mechanically-linked Polymers" G J Clarkson, D A Leigh and R A Smith, Curr Opin Solid State & Mater Sci., 3, 579-584 (1998).

"Controlling the Frequency of Macrocyclic Ring Rotation in Benzylic Amide [2]Catenanes " D A Leigh, A Murphy, J P Smart, M S Deleuze, F Zerbetto, J Am Chem Soc., 120, 6458-6467(1998).

"Inelastic Neutron Scattering of Large Molecular Systems: The Case of the Original Benzylic Amide [2]Catenane" R Caciuffo, A Degli Esposti, M S Deleuze, D A Leigh, A Murphy, B Paci, S F Parker and F Zerbetto, J Chem Phys., 109, 11094-11100 (1998).

"Experimental and Theoretical Studies of the Low-lying Electronic States of the Simplest Benzylic Amide [2]Catenane" A M Brouwer, W J Buma, R Caudano, M Fanti, C A Fustin, D A Leigh, A Murphy, P Rudolf, F Zerbetto and J M Zwier, Chem Phys., 238, 421-428 (1998).

"High-Frequency Vibrations of the Simplest Benzylic Amide [2]Catenane"M Fanti, C-A Fustin, D A Leigh, A Murphy, P Rudolf, R Caudano, R Zamboni, F Zerbetto, J Phys Chem A., 102, 5782-5788 (1998).

"Thin Films of Benzylic Amide [2]Catenane as a Novel Versatile Photonic Material", T Gase, D Grando, P A Chollet, F Kajzar, A Lorin, D Tetard and D A Leigh, Photonics Sci News., 3,16-21 (1998).

[Front cover “Benzylic Amide Catenanes as Novel Versatile Photonic Materials”, Photonics Sci News, issue 4, 3, 1998.]

"Growth and Characterization of Benzylic Amide [2]Catenane Thin Films", C A Fustin, P Rudolf, A F Taminiaux, F Zerbetto, D A Leigh and R Caudano, Thin Solid Films, 329, 321-325 (1998).

"Study of Energy Gap and Electronic Transitions in Model Polymer Systems: Electronic vs. Optical Excitations", J J Pireaux, G Gensterblum, C Grégoire, B Y Han, K Hevesi, C A Fustin, P Rudolf, L M Yu, R Caudano, D A Leigh and F Zerbetto, Sci Tech Polymers and Adv Mater (Ed. P N Prasad), Plenum Press, New York (1998).

1997

"Peptide-based Molecular Shuttles", A S Lane, D A Leigh and A Murphy, J Am Chem Soc 119, 11092-11093 (1997).

[For a highlight see "Molecular Shuttles", Science News, May 1997.]

"Glycylglycine Rotaxanes - The Hydrogen Bond-Directed Assembly of Synthetic Peptide Rotaxanes ", D A Leigh, A Murphy, J P Smart and A M Z Slawin, Angew Chem, Int Ed Engl 36, 728-732 (1997).

"Studies of Multiple-chain Alkylaminomethyl þ-Cyanophenol Derivatives for Langmuir-Blodgett Films", K A Longstaff, D A Leigh and R W Munn, Adv Mat Optics Elec., 7, 295-305 (1997).

1996

"Catenane Chameleons: Environment-Sensitive Translational Isomerism in Amphiphilic Benzylic Amide [2]Catenanes", D A Leigh, K Moody, J P Smart, K J Watson and A M Z Slawin, Angew Chem, Int Ed Engl., 35, 306-310 (1996).

"The Synthesis and Solubilization of Amide Macrocycles via Rotaxane Formation" A G Johnston, D A Leigh, A Murphy, J P Smart and M D Deegan, J Am Chem Soc., 118, 10662-10663 (1996)

"Crystallization-Resistant Photorefractive Polymer Composite with High Diffraction Efficiency and Reproducibility", A M Cox, R D Blackburn, D P West, T A King, F A Wade and D A Leigh, Appl Phys Lett., 68, 2801-2803 (1996).

"Crystallization-Resistant Photorefractive Materials", A M Cox, F A Wade, R D Blackburn, D P West, D A Leigh and T A King, UK Patent No. 9609876 , 11th May, 1996.

"The Programmed Assembly-Controlled Disassembly of [2]Rotaxanes as a Strategy in Synthesis: The Preparation of a Chemical Sensor for CO₂", A G Johnston, D A Leigh, A Murphy and J P Smart, Bull Chem Soc Belg., 105, 721-727 (1996).

"Fast Atom Bombardment Mass Spectrometry as a Toll for the Rapid Determination of Enantioselective Binding of Methylated Cyclodextrins", S N Davey, D A Leigh, J P Smart, L W Tetler and A M Truscello, Carbohydr Res., 290, 117-123 (1996).

"CAChe Molecular Modelling", D A Leigh, J Mol Struct (Theochem)., 262, 149-150 (1996).

1995

"Facile Synthesis and Solid State Structure of a Benzylic Amide [2]Catenane" A G Johnston, D A Leigh, R J Pritchard and M D Deegan, Angew Chem, Int Ed Engl., 34, 1209-1212 (1995).

[Front cover, Angew Chem, Int Ed Engl, issue 11, 34 1995; for highlights of this paper see Chem & Ind, June and July 1995.]

"Structurally Diverse and Dynamically Versatile Benzylic Amide [2]Catenanes Assembled Directly from Commercially Available Precursors" A G Johnston, D A Leigh, L Nezhat, J P Smart and M D Deegan, Angew Chem, Int Ed Engl., 34, 1212-1216 (1995).

"Intermolecular Aglycon Transfer of Ethyl 1-Thiorhamnopyranosides under Koenigs-Knorr Glycosylation Conditions", D A Leigh, J P Smart and A M Truscello, Carbohydr Res., 276, 417-424 (1995).

"Polymers for the Decaffeination of Green Coffee Extract", P Hay, D A Leigh and R Liardon, Europatent No. 95203394.2, 7 Dec, 1995.

"Second Harmonic Generation from Langmuir-Blodgett Films of Fullerene Azacrown Ethers", D A Leigh, F A Wade, T A King, D West and G S Bahra, Langmuir, 11, 2334-2336 (1995).

1994

"C₆₀-Azacrown Ethers: the first Monoanimated Fullerene Derivatives", S N Davey, D A Leigh, A E Moody, L W Tetler and F A Wade, J Chem Soc, Chem Commun., 397-398 (1994).

"Kinetically-controlled Regioselective Silylation of Polyols via Dibutylstannylendiyl Acetals", D A Leigh, R P Martin, J P Smart and A M Truscello, J Chem Soc, Chem Commun., 1373-1374 (1994).

"Unusual Host-Guest ∏-Arene∙∙∙H bonding in a 'Hooded' Cavitand: the First Solid-state Structure of a Calix[4]resorcinarene with Underivatised Hydroxy Groups", D A Leigh, P Linnane, R G Pritchard and G Jackson, J Chem Soc, Chem Commun., 389-390 (1994).

"Endohedral Complexation of Helium Atoms by Derivatised Fullerenes", S N Davey, D A Leigh, A E Moody and L W Tetler, J Chem Soc, Chem Commun., 7-8 (1994).

"Improved Second Harmonic Generation from Langmuir-Blodgett Films of an Azacrown Ether Fullerene Derivative", D A Leigh, F A Wade, T A King, D West and G S Bahra, Mat Res Soc Symp Proc., 349, 343-348 (1994).

"2,7-Dimethyl-3,5-octadiyne-2,7-diol Dichloromethane Solvate: a Clathrate Comprising Hydrogen-Bonded Supramolecular Tunnels Containing Dichloromethane Guest Molecules", D A Leigh, A E Moody and R G Pritchard, Acta Cryst., C50, 129-131 (1994).

1993

"The Confinement of Buckminsterfullerene in One-Dimensional Channels", M W Anderson, J Shi, D A Leigh, A E Moody, F A Wade, B Hamilton and S W Carr, J Chem Soc, Chem Commun., 533-536 (1993).

"Broad-band Visible Light Emission from C₆₀ Molecules Confined in Molecular Cage Materials", B Hamilton, J S Rimmer, M W Anderson and D A Leigh, Adv Mater., 5, 583-585 (1993).

[For highlights see "Bottle and Glow Fullerenes", Science, 258, 1886 (1992) and "Rainbow-Coloured Buckyballs Light Up the Lab", New Scientist, 15, 1st May 1993.]

"Unorthodox Rate Enhancement in the Mannich Reaction of para-Substituted Phenols Containing Electron-Withdrawing Groups", D A Leigh, P Linnane and G Jackson, Tetrahedron Lett., 34, 5639-5640 (1993).

"Mannich Base Wax Crystal Modifying Agents", P Linnane, D A Leigh and G Jackson, UK patent 3476334 (1993).

"The Regioselective tert-Butyldimethylsilyation of the 6'-Hydroxyl Group of Lactose Derivatives via their Dibutylstannylene Acetals", A Glen, D A Leigh, R P Martin, J P Smart and A M Truscello, Carbohydrate Res., 248, 365-369 (1993).

[For a highlight see "New Properties of Stannylenes: The Regioselective tert-Butylmethylsiylation of the 6'Hydroxyl Group of Lactose Derivatives via their Dibutylstannylene Acetals ", Chemtracts - Org Chem., 315-319 (1993).]

"Design of Langmuir-Blodgett Films for Non-Linear Optics", A Baggaley, M Bishop, J H R Clarke, L E Davis, T A King, D A Leigh, F R Mayers, A Mohebati, R W Munn, M M Shabat, O Szczur, D West and J O Williams, Mol Cryst Liq Cryst., 235, 201-208 (1993).

"Mass Spectrometry of Animated Fullerene Derivatives", S N Davey, D A Leigh, A E Moody and L W Tetler, Org Mass Spectrometry., 28, 559-563 (1993).

1992

"Fullerenes: A Light Source Material", M W Anderson, B Hamilton and D A Leigh, UK Patent No. 9225831, 10 Dec 1992.

"A Novel Synthesis of Substituted 12-H-Quino-(2,1-B)(1,3)- Benzodiazepin-4-one Derivatives", M C Aversa, P Bonaccorsi, P Giannetto, R G Pritchard, B Beagley, A Truscello and D A Leigh, J Heterocyclic Chem., 28, 318-323 (1992).

1990

"The In Situ Activation of Thioglycosides with Bromine: An Improved Glycosylation Method", J O Kihlberg, D A Leigh and D R Bundle, J Org Chem., 55, 2860-2863 (1990).

1989

"Conformational Analysis of Some 11,12-Dihydrodibenz[B,F][1,5]-oxozocin-6-one Derivatives by NMR Spectroscopy", M C Aversa, P Bonaccorsi, P Giannetto and D A Leigh, Tetrahedron, 45, 6857-6866 (1989).

"Cycloaddition Reactions of 2,3-Dihydro-1H-1,4-diazepines with Nitrile Oxides and Imines. Synthesis of bis[1,2,4]Oxadiazolo- and bis[1,2,4]Triazolo[1,4]diazepine Derivatives", M C Aversa, P Bonaccorsi, P Giannetto and D A Leigh, J Heterocyclic Chem., 26, 1619-1622 (1989).

1988

"The Complexation Properties of Some Unnatural and Natural Macrocyclic Trichothecenes", D W Anderson, P R Ashton, R M Black, D A Leigh, A M Z Slawin, J F Stoddart and D J Williams, J Chem Soc, Chem Commun., 904-908 (1988).

1987

"The Facile Conversion of T-2 Toxin and Neosolaniol into Anguidine", D W Anderson, R M Black, D A Leigh, J F Stoddart and N E Williams, Tetrahedron Letts., 28, 2661-2662 (1987).

"Novel 3,4- and 8,15-Polyether Analogues of Macrocyclic Trichothecenes", D W Anderson, R M Black, D A Leigh and J F Stoddart, Tetrahedron Letts., 28, 2657-2660 (1987).

"Novel 4,15-Polyether Analogues of Macrocyclic Trichothecenes", D W Anderson, R M Black, D A Leigh, J F Stoddart and N E Williams, Tetrahedron Letts., 28, 2653-2656 (1987).

www.rotaxane.net